Mandibular primitive neuroectodermal tumor in an adult dog

This is the report of a mandibular neuroectodermal/ewing sarcoma in an 8-year-old male cross breed dog that is unique because of tumor origin location. Pedunculated, ulcerative, firm 6.0 x 4.0 x 5.5 cm tumor mass effaced the bone at the rostral part of the mandible and had a white-sanguineous color at cross section appearance. Histopathologically, small round blue cell tumor was diagnosed. Immunohistochemically, tumor cells were positive for vimentin, S100 and Glial fibrillary acidic protein [GFAP] and negative for neuron specific enolase [NSE] and desmin. Mandibular location is a rare event in these types of tumors

Penile fibrosarcoma tumor in a bull

This is a report of a penile fibrosarcoma in a two-year-old crossbred Holstein bull. The ulcerated tumor mass with dimensions of 7 x 9x 6.5 cm, was enveloped the glans and body of the penis. It had a white-gray color at cross section appearance. There was no metastatic evidence of regional lymph node enlargement. Histopathologically, elongated spindle-shpaed cells arranged densely in the interwoven pattern had a low rat of mitosis with oddly-shaped nuclei and pleomorphism. Immunohistochemically, the neoplastic cells were positive for vimentin and S100, but negative for alpha-smooth muscle actin, desmin, C-KT and GFAP